Microdose GLP-1 · Compounded
Microdose Semaglutide
A lower, maintenance-style dose of compounded semaglutide as a once-weekly injection, billed month to month, for holding your results.
- Lower, maintenance-style dose
- Once-weekly injection
- Month to month, cancel anytime
- Provider-reviewed before prescribed
Every plan includes
- Licensed provider review of your intake
- Compounded microdose semaglutide shipped from a licensed pharmacy when prescribed
- Unlimited messaging with your care team and provider
- Free shipping on every order
- Dose adjustments as your provider directs
What it is and how it works
Microdosing means using a lower dose of a GLP-1 medication than a typical full-dose weight-loss plan. Many women use it to maintain their results after reaching their goal.
Microdose semaglutide is taken as a once-weekly injection at a reduced dose. It is a maintenance-style approach, not Josie’s primary weight-loss pathway.
It is compounded by a licensed pharmacy and billed month to month, so you can stay flexible. A Josie provider reviews your intake before any prescription is issued.
Who it’s for
May be a fit if you
- Have reached your weight goal and want to maintain
- Want a lower-dose, maintenance-style approach
- Prefer month-to-month flexibility
- Want licensed provider oversight and ongoing support
Not the right fit if you
- Are just starting and want active weight loss (consider full-dose GLP-1)
- Have a personal or family history of medullary thyroid carcinoma or MEN 2
- Are pregnant, trying to conceive, or breastfeeding
- Are advised against GLP-1 care by your provider
Eligibility is always determined by a licensed provider after reviewing your intake.
How to take it
- 1Your provider confirms your maintenance dose and schedule.
- 2Inject once weekly, on the same day each week, as directed.
- 3Stay in touch with your care team to adjust as your needs change.
- 4Reorder month to month for as long as it fits your plan.
Safety, risks & side effects
GLP-1 medications carry real risks. Review them with a licensed provider and read the full prescribing information before starting.
Boxed warning: In rodent studies, semaglutide caused thyroid C-cell tumors. It is not known whether it causes these tumors, including medullary thyroid carcinoma (MTC), in humans. Do not use if you or a family member has had MTC or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
Common side effects
- Nausea
- Diarrhea or constipation
- Vomiting
- Abdominal pain
- Fatigue
Serious risks
- Pancreatitis (inflammation of the pancreas)
- Gallbladder problems
- Low blood sugar, especially with other diabetes medicines
- Kidney problems related to dehydration
- Serious allergic reactions
Do not use if you have
- Personal or family history of medullary thyroid carcinoma
- Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
- Known serious allergy to semaglutide
- Pregnancy or breastfeeding
Frequently asked questions
What is microdosing?
Microdosing means using a lower dose of a GLP-1 medication than a typical full-dose weight-loss plan. At Josie it is most often used to maintain results after reaching a goal.
Who is microdose semaglutide for?
It is a maintenance-style option, generally for women who have already reached their weight goal and want to hold their results with a lower dose. A provider helps you decide if it fits your stage.
How is it different from full-dose semaglutide?
It uses the same molecule at a lower dose. Full-dose compounded semaglutide is the active weight-management option, while microdose is a maintenance-style approach. Microdose is not Josie’s primary weight-loss pathway.
How much does it cost, and is there a membership fee?
Microdose semaglutide is billed month to month at the price shown above, which includes your provider review, ongoing messaging, and shipping. There is no separate membership fee, and you can cancel anytime.
Is there a consultation fee?
There is no upfront fee to complete your intake. A $80 consultation fee applies only if a licensed provider approves your care plan and you then choose not to proceed with medication.
Which US states is Josie available in?
Josie is available in all 50 US states.
Which pharmacy fills my prescription?
If a provider prescribes microdose semaglutide, it is prepared and shipped by a licensed US compounding pharmacy. Month-to-month plans are filled by Strive Pharmacy, only if offered in your state. Reach out to our customer support team at team@joinjosie.com to see if Strive Pharmacy delivers where you live. Clear instructions are included with your order.
Is microdose semaglutide FDA approved?
No. Compounded and microdose GLP-1 medications are not FDA approved, and the FDA does not review them for safety, effectiveness, or quality before marketing. A licensed provider determines whether it is appropriate for you.
How do I start?
Complete the online intake. A licensed Josie provider reviews your history and, if appropriate, prescribes your plan, which is shipped from a licensed pharmacy.
Compounded and microdose GLP-1 medications are not FDA approved. The FDA does not review compounded medications for safety, effectiveness, or quality before marketing.
Microdose GLP-1 is a maintenance-style approach and is not Josie’s primary weight-loss pathway. Medications are only issued when clinically appropriate after a provider evaluation.
What to Expect at Josie
- Complete your intake online, from anywhere
- Provider review by Josie's licensed clinicians, supervised by Dr. Ana Lisa Carr, MD
- Transparent program pricing
- Medication shipped from a licensed pharmacy or compounding pharmacy when prescribed